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Restriction beyond the restriction point: mitogen requirement for G(2 )passage
Cell proliferation is dependent on mitogenic signalling. When absent, normal cells cannot pass the G(1 )restriction point, resulting in cell cycle arrest. Passage through the G(1 )restriction point involves inactivation of the retinoblastoma protein family. Consequently, loss of the retinoblastoma p...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2006
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1481568/ https://www.ncbi.nlm.nih.gov/pubmed/16759363 http://dx.doi.org/10.1186/1747-1028-1-8 |