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Role of transcription factor Sp1 and CpG methylation on the regulation of the human podocalyxin gene promoter

BACKGROUND: Podocalyxin (podxl) is a heavily glycosylated transmembrane protein mainly found on the apical membrane of rat podocytes and also in endothelial, hematopoietic, and tumor cells. Despite of its interest no much is known about the transcriptional regulation of podxl in different cells. Thu...

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Detalles Bibliográficos
Autores principales: Butta, Nora, Larrucea, Susana, Alonso, Sonia, Rodriguez, Ramón B, Arias-Salgado, Elena G, Ayuso, Matilde S, González-Manchón, Consuelo, Parrilla, Roberto
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1481587/
https://www.ncbi.nlm.nih.gov/pubmed/16684343
http://dx.doi.org/10.1186/1471-2199-7-17