Compensation by tumor suppressor genes during retinal development in mice and humans

BACKGROUND: The RB1 gene was the first tumor suppressor gene cloned from humans by studying genetic lesions in families with retinoblastoma. Children who inherit one defective copy of the RB1 gene have an increased susceptibility to retinoblastoma. Several years after the identification of the human...

Descripción completa

Detalles Bibliográficos
Autores principales: Donovan, Stacy L, Schweers, Brett, Martins, Rodrigo, Johnson, Dianna, Dyer, Michael A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1481602/
https://www.ncbi.nlm.nih.gov/pubmed/16672052
http://dx.doi.org/10.1186/1741-7007-4-14

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1481602/
https://www.ncbi.nlm.nih.gov/pubmed/16672052
http://dx.doi.org/10.1186/1741-7007-4-14

Ejemplares similares