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Compensation by tumor suppressor genes during retinal development in mice and humans
BACKGROUND: The RB1 gene was the first tumor suppressor gene cloned from humans by studying genetic lesions in families with retinoblastoma. Children who inherit one defective copy of the RB1 gene have an increased susceptibility to retinoblastoma. Several years after the identification of the human...
Autores principales: | Donovan, Stacy L, Schweers, Brett, Martins, Rodrigo, Johnson, Dianna, Dyer, Michael A |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1481602/ https://www.ncbi.nlm.nih.gov/pubmed/16672052 http://dx.doi.org/10.1186/1741-7007-4-14 |
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