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Expression and processing of the Hepatitis E virus ORF1 nonstructural polyprotein
BACKGROUND: The ORF1 of hepatitis E virus (HEV) encodes a nonstructural polyprotein of ~186 kDa that has putative domains for four enzymes: a methyltransferase, a papain-like cysteine protease, a RNA helicase and a RNA dependent RNA polymerase. In the absence of a culture system for HEV, the ORF1 ex...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1481634/ https://www.ncbi.nlm.nih.gov/pubmed/16725054 http://dx.doi.org/10.1186/1743-422X-3-38 |