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Expression and processing of the Hepatitis E virus ORF1 nonstructural polyprotein

BACKGROUND: The ORF1 of hepatitis E virus (HEV) encodes a nonstructural polyprotein of ~186 kDa that has putative domains for four enzymes: a methyltransferase, a papain-like cysteine protease, a RNA helicase and a RNA dependent RNA polymerase. In the absence of a culture system for HEV, the ORF1 ex...

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Detalles Bibliográficos
Autores principales:	Sehgal, Deepak, Thomas, Saijo, Chakraborty, Mahua, Jameel, Shahid
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2006
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1481634/ https://www.ncbi.nlm.nih.gov/pubmed/16725054 http://dx.doi.org/10.1186/1743-422X-3-38

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