Inhibition of constitutively active Jak-Stat pathway suppresses cell growth of human T-cell leukemia virus type 1-infected T-cell lines and primary adult T-cell leukemia cells

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BACKGROUND: Human T-cell leukemia virus type 1 (HTLV-1), the etiologic agent for adult T-cell leukemia (ATL), induces cytokine-independent proliferation of T-cells, associated with the acquisition of constitutive activation of Janus kinases (Jak) and signal transducers and activators of transcriptio...

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Detalles Bibliográficos
Autores principales: Tomita, Mariko, Kawakami, Hirochika, Uchihara, Jun-nosuke, Okudaira, Taeko, Masuda, Masato, Matsuda, Takehiro, Tanaka, Yuetsu, Ohshiro, Kazuiku, Mori, Naoki
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1483830/
https://www.ncbi.nlm.nih.gov/pubmed/16603085
http://dx.doi.org/10.1186/1742-4690-3-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1483830/
https://www.ncbi.nlm.nih.gov/pubmed/16603085
http://dx.doi.org/10.1186/1742-4690-3-22

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