Two Membrane-Associated Tyrosine Phosphatase Homologs Potentiate C. elegans AKT-1/PKB Signaling

Akt/protein kinase B (PKB) functions in conserved signaling cascades that regulate growth and metabolism. In humans, Akt/PKB is dysregulated in diabetes and cancer; in Caenorhabditis elegans, Akt/PKB functions in an insulin-like signaling pathway to regulate larval development. To identify molecules...

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Detalles Bibliográficos
Autores principales: Hu, Patrick J, Xu, Jinling, Ruvkun, Gary
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1487177/
https://www.ncbi.nlm.nih.gov/pubmed/16839187
http://dx.doi.org/10.1371/journal.pgen.0020099

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1487177/
https://www.ncbi.nlm.nih.gov/pubmed/16839187
http://dx.doi.org/10.1371/journal.pgen.0020099

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