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Human Imprinted Chromosomal Regions Are Historical Hot-Spots of Recombination

Human recombination rates vary along the chromosomes as well as between the two sexes. There is growing evidence that epigenetic factors may have an important influence on recombination rates, as well as on crossover position. Using both public database analysis and wet-bench approaches, we revisite...

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Detalles Bibliográficos
Autores principales: Sandovici, Ionel, Kassovska-Bratinova, Sacha, Vaughan, Joe E, Stewart, Rae, Leppert, Mark, Sapienza, Carmen
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1487178/
https://www.ncbi.nlm.nih.gov/pubmed/16839189
http://dx.doi.org/10.1371/journal.pgen.0020101