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A clinical genetic method to identify mechanisms by which pain causes depression and anxiety

BACKGROUND: Pain patients are often depressed and anxious, and benefit less from psychotropic drugs than pain-free patients. We hypothesize that this partial resistance is due to the unique neurochemical contribution to mood by afferent pain projections through the spino-parabrachial-hypothalamic-am...

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Detalles Bibliográficos
Autores principales: Max, Mitchell B, Wu, Tianxia, Atlas, Steven J, Edwards, Robert R, Haythornthwaite, Jennifer A, Bollettino, Antonella F, Hipp, Heather S, McKnight, Colin D, Osman, Inge A, Crawford, Erin N, Pao, Maryland, Nejim, Jemiel, Kingman, Albert, Aisen, Daniel C, Scully, Michele A, Keller, Robert B, Goldman, David, Belfer, Inna
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1488826/
https://www.ncbi.nlm.nih.gov/pubmed/16623937
http://dx.doi.org/10.1186/1744-8069-2-14