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A clinical genetic method to identify mechanisms by which pain causes depression and anxiety
BACKGROUND: Pain patients are often depressed and anxious, and benefit less from psychotropic drugs than pain-free patients. We hypothesize that this partial resistance is due to the unique neurochemical contribution to mood by afferent pain projections through the spino-parabrachial-hypothalamic-am...
Autores principales: | Max, Mitchell B, Wu, Tianxia, Atlas, Steven J, Edwards, Robert R, Haythornthwaite, Jennifer A, Bollettino, Antonella F, Hipp, Heather S, McKnight, Colin D, Osman, Inge A, Crawford, Erin N, Pao, Maryland, Nejim, Jemiel, Kingman, Albert, Aisen, Daniel C, Scully, Michele A, Keller, Robert B, Goldman, David, Belfer, Inna |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1488826/ https://www.ncbi.nlm.nih.gov/pubmed/16623937 http://dx.doi.org/10.1186/1744-8069-2-14 |
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