Cargando…

CysLT(1 )receptor-induced human airway smooth muscle cells proliferation requires ROS generation, EGF receptor transactivation and ERK1/2 phosphorylation

BACKGROUND: Cysteine-containing leukotrienes (cysteinyl-LTs) are pivotal inflammatory mediators that play important roles in the pathophysiology of asthma, allergic rhinitis, and other inflammatory conditions. In particular, cysteinyl-LTs exert a variety of effects with relevance to the aetiology of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ravasi, Saula, Citro, Simona, Viviani, Barbara, Capra, Valérie, Rovati, G Enrico
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2006
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1488842/ https://www.ncbi.nlm.nih.gov/pubmed/16553950 http://dx.doi.org/10.1186/1465-9921-7-42

Ejemplares similares

Expression of cysLT1 and cysLT2 Receptor in Chronic Hyperplastic Eosinophilic Sinusitis
por: Ouyang, Yuhui, et al.
Publicado: (2009)

Cysteinyl leukotrienes regulate endothelial cell inflammatory and proliferative signals through CysLT(2) and CysLT(1) receptors
por: Duah, Ernest, et al.
Publicado: (2013)

Baicalin Ameliorates Radiation-Induced Lung Injury by Inhibiting the CysLTs/CysLT1 Signaling Pathway
por: Bao, Wu-An, et al.
Publicado: (2022)

CysLT1 receptor antagonist alleviates pathogenesis of collagen-induced arthritis mouse model
por: Xu, Minwen, et al.
Publicado: (2017)

The CysLT(2)R receptor mediates leukotriene C(4)-driven acute and chronic itch
por: Voisin, Tiphaine, et al.
Publicado: (2021)

Cysteinyl leukotriene signaling through perinuclear CysLT(1) receptors on vascular smooth muscle cells transduces nuclear calcium signaling and alterations of gene expression
por: Eaton, Alison, et al.
Publicado: (2012)

CysLT(1)R Antagonists Inhibit Tumor Growth in a Xenograft Model of Colon Cancer
por: Savari, Sayeh, et al.
Publicado: (2013)

Synthesis of tenascin and laminin beta2 chain in human bronchial epithelial cells is enhanced by cysteinyl leukotrienes via CysLT(1 )receptor
por: Altraja, Siiri, et al.
Publicado: (2008)

Blockade of Platelet CysLT1R Receptor with Zafirlukast Counteracts Platelet Protumoral Action and Prevents Breast Cancer Metastasis to Bone and Lung
por: Saier, Lou, et al.
Publicado: (2022)

Differential Inhibitory Effects of CysLT(1) Receptor Antagonists on P2Y(6) Receptor-Mediated Signaling and Ion Transport in Human Bronchial Epithelia
por: Lau, Wendy Ka-hoi, et al.
Publicado: (2011)

Leukotriene D(4) induces chemotaxis in human eosinophilc cell line, EoL-1 cells via CysLT1 receptor activation
por: Shirasaki, Hideaki, et al.
Publicado: (2017)

Mechanisims of asthma and allergic disease – 1084. Localization and up-regulation of CysLT2 receptorin perennial allergic rhinitis
por: Shirasaki, Hideaki, et al.
Publicado: (2013)

Discovery of a Potent and Orally Active Dual GPBAR1/CysLT(1)R Modulator for the Treatment of Metabolic Fatty Liver Disease
por: Fiorucci, Stefano, et al.
Publicado: (2022)

CRISPR/Cas9-mediated CysLT1R deletion reverses synaptic failure, amyloidosis and cognitive impairment in APP/PS1 mice
por: Chen, Fang, et al.
Publicado: (2021)

Hippocampal CysLT1R overexpression or activation accelerates memory deficits, synaptic dysfunction, and amyloidogenesis in young APP/PS1 transgenic mice
por: Fang, Shun-Chang, et al.
Publicado: (2021)

RNA-binding protein RBM3 intrinsically suppresses lung innate lymphoid cell activation and inflammation partially through CysLT1R
por: Badrani, Jana H., et al.
Publicado: (2022)

CysLT(2)R Antagonist HAMI 3379 Ameliorates Post-Stroke Depression through NLRP3 Inflammasome/Pyroptosis Pathway in Gerbils
por: Zhou, Li, et al.
Publicado: (2022)

EGF Receptor Transactivation by Endothelin-1 Increased CHSY-1 Mediated by NADPH Oxidase and Phosphorylation of ERK1/2
por: Babaahmadi-Rezaei, Hossein, et al.
Publicado: (2021)

The metalloprotease Kuzbanian (ADAM10) mediates the transactivation of EGF receptor by G protein–coupled receptors
por: Yan, Yibing, et al.
Publicado: (2002)

134 Expression and Localization of CYSLT2 Receptor in Human Nasal Mucosa
por: Hideaki, Shirasaki, et al.
Publicado: (2012)

Cysteinyl-leukotrienes in the regulation of β(2)-adrenoceptor function: an in vitro model of asthma
por: Rovati, G Enrico, et al.
Publicado: (2006)

Visualization of the binding between gintonin, a Panax ginseng-derived LPA receptor ligand, and the LPA receptor subtypes and transactivation of the EGF receptor
por: Choi, Sun-Hye, et al.
Publicado: (2022)

A(1) adenosine receptor–stimulated exocytosis in bladder umbrella cells requires phosphorylation of ADAM17 Ser-811 and EGF receptor transactivation
por: Prakasam, H. Sandeep, et al.
Publicado: (2014)

Cysteinyl-Leukotriene Receptors and Cellular Signals
por: Rovati, G. Enrico, et al.
Publicado: (2007)

c-Src-dependent EGF receptor transactivation contributes to ET-1-induced COX-2 expression in brain microvascular endothelial cells
por: Hsieh, Hsi-Lung, et al.
Publicado: (2012)

Caveolin-1 is required for TGF-β-induced transactivation of the EGF receptor pathway in hepatocytes through the activation of the metalloprotease TACE/ADAM17
por: Moreno-Càceres, J, et al.
Publicado: (2014)

Lipopolysaccharide acting via toll-like receptor 4 transactivates the TGF-β receptor in vascular smooth muscle cells
por: Afroz, Rizwana, et al.
Publicado: (2022)

Gαq Is the Specific Mediator of PAR-1 Transactivation of Kinase Receptors in Vascular Smooth Muscle Cells
por: Kamato, Danielle, et al.
Publicado: (2022)

Transactivation of the estrogen receptor promoter by BRCA1
por: Archey, William B., et al.
Publicado: (2017)

Participation of Tom1L1 in EGF-stimulated endocytosis of EGF receptor
por: Liu, Ning Sheng, et al.
Publicado: (2009)

Helicobacter pylori-Induced HB-EGF Upregulates Gastrin Expression via the EGF Receptor, C-Raf, Mek1, and Erk2 in the MAPK Pathway
por: Gunawardhana, Niluka, et al.
Publicado: (2018)

Tumor necrosis factor-alpha induces VCAM-1-mediated inflammation via c-Src-dependent transactivation of EGF receptors in human cardiac fibroblasts
por: Lin, Chih-Chung, et al.
Publicado: (2015)

A Novel Urotensin II Receptor Antagonist, KR-36996 Inhibits Smooth Muscle Proliferation through ERK/ROS Pathway
por: Kim, Tae-Ho, et al.
Publicado: (2017)

RNA sequencing to determine the contribution of kinase receptor transactivation to G protein coupled receptor signalling in vascular smooth muscle cells
por: Kamato, Danielle, et al.
Publicado: (2017)

Independent β-Arrestin2 and G(q)/Protein Kinase Cζ Pathways for ERK Stimulated by Angiotensin Type 1A Receptors in Vascular Smooth Muscle Cells Converge on Transactivation of the Epidermal Growth Factor Receptor
por: Kim, Jihee, et al.
Publicado: (2009)

Local signaling by the EGF receptor
por: Kempiak, Stephan J., et al.
Publicado: (2003)

Whole-Genome Shotgun Sequences of Salmonella enterica Serovar Typhimurium Lilleengen Type Strains LT1, LT18, LT19, LT20, LT21, and LT22
por: Kazmierczak, Robert A., et al.
Publicado: (2017)

GABA(B) Receptor Subunit GB1 at the Cell Surface Independently Activates ERK1/2 through IGF-1R Transactivation
por: Baloucoune, Guillaume A., et al.
Publicado: (2012)

Mechanism of Allosteric Modulation of the Cys-loop Receptors
por: Chang, Yongchang, et al.
Publicado: (2010)

Principles of agonist recognition in Cys-loop receptors
por: Lynagh, Timothy, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_i41ihbb7nedebpl0bh0s21gn2d