Nucleotide sequence analyses of the MRP1 gene in four populations suggest negative selection on its coding region

BACKGROUND: The MRP1 gene encodes the 190 kDa multidrug resistance-associated protein 1 (MRP1/ABCC1) and effluxes diverse drugs and xenobiotics. Sequence variations within this gene might account for differences in drug response in different individuals. To facilitate association studies of this gen...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Zihua, Sew, Pui-Hoon, Ambrose, Helen, Ryan, Stephen, Chong, Samuel S, Lee, Edmund JD, Lee, Caroline GL
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1488846/
https://www.ncbi.nlm.nih.gov/pubmed/16684361
http://dx.doi.org/10.1186/1471-2164-7-111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1488846/
https://www.ncbi.nlm.nih.gov/pubmed/16684361
http://dx.doi.org/10.1186/1471-2164-7-111

Ejemplares similares