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Nucleotide sequence analyses of the MRP1 gene in four populations suggest negative selection on its coding region

BACKGROUND: The MRP1 gene encodes the 190 kDa multidrug resistance-associated protein 1 (MRP1/ABCC1) and effluxes diverse drugs and xenobiotics. Sequence variations within this gene might account for differences in drug response in different individuals. To facilitate association studies of this gen...

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Detalles Bibliográficos
Autores principales:	Wang, Zihua, Sew, Pui-Hoon, Ambrose, Helen, Ryan, Stephen, Chong, Samuel S, Lee, Edmund JD, Lee, Caroline GL
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2006
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1488846/ https://www.ncbi.nlm.nih.gov/pubmed/16684361 http://dx.doi.org/10.1186/1471-2164-7-111

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