Rapid and sensitive detection of CpG-methylation using methyl-binding (MB)-PCR

Methylation of CpG islands is associated with transcriptional repression and, in cancer, leads to the abnormal silencing of tumor suppressor genes. We have developed a novel technique for detecting CpG-methylated DNA termed methyl-binding (MB)-PCR. This technique utilizes a recombinant protein with...

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Detalles Bibliográficos
Autores principales: Gebhard, Claudia, Schwarzfischer, Lucia, Pham, Thu Hang, Andreesen, Reinhard, Mackensen, Andreas, Rehli, Michael
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1488883/
https://www.ncbi.nlm.nih.gov/pubmed/16822855
http://dx.doi.org/10.1093/nar/gkl437

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1488883/
https://www.ncbi.nlm.nih.gov/pubmed/16822855
http://dx.doi.org/10.1093/nar/gkl437

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