RTS,S/AS02A Malaria Vaccine Does Not Induce Parasite CSP T Cell Epitope Selection and Reduces Multiplicity of Infection

OBJECTIVE: The candidate malaria vaccine RTS,S/AS02A is a recombinant protein containing part of the circumsporozoite protein (CSP) sequence of Plasmodium falciparum, linked to the hepatitis B surface antigen and formulated in the proprietary adjuvant system AS02A. In a recent trial conducted in chi...

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Detalles Bibliográficos
Autores principales: Enosse, Sonia, Dobaño, Carlota, Quelhas, Diana, Aponte, John J, Lievens, Marc, Leach, Amanda, Sacarlal, Jahit, Greenwood, Brian, Milman, Jessica, Dubovsky, Filip, Cohen, Joe, Thompson, Ricardo, Ballou, W. Ripley, Alonso, Pedro L, Conway, David J, Sutherland, Colin J
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1488895/
https://www.ncbi.nlm.nih.gov/pubmed/16871327
http://dx.doi.org/10.1371/journal.pctr.0010005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1488895/
https://www.ncbi.nlm.nih.gov/pubmed/16871327
http://dx.doi.org/10.1371/journal.pctr.0010005

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