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Modeling the effects of a Staphylococcal Enterotoxin B (SEB) on the apoptosis pathway

BACKGROUND: The lack of detailed understanding of the mechanism of action of many biowarfare agents poses an immediate challenge to biodefense efforts. Many potential bioweapons have been shown to affect the cellular pathways controlling apoptosis [1-4]. For example, pathogen-produced exotoxins such...

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Detalles Bibliográficos
Autores principales: Higgs, Brandon W, Dileo, John, Chang, Wenling E, Smith, Haley B, Peters, Olivia J, Hammamieh, Rasha, Jett, Marti, Feidler, Jordan C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1489937/
https://www.ncbi.nlm.nih.gov/pubmed/16737533
http://dx.doi.org/10.1186/1471-2180-6-48