Optimal Step Length EM Algorithm (OSLEM) for the estimation of haplotype frequency and its application in lipoprotein lipase genotyping

BACKGROUND: Haplotype based linkage disequilibrium (LD) mapping has become a powerful and cost-effective method for performing genetic association studies, particularly in the search for genetic markers in linkage disequilibrium with complex disease loci. Various methods (e.g. Monte-Carlo (Gibbs sam...

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Detalles Bibliográficos
Autores principales: Zhang, Peisen, Sheng, Huitao, Morabia, Alfredo, Gilliam, T Conrad
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC149347/
https://www.ncbi.nlm.nih.gov/pubmed/12529185
http://dx.doi.org/10.1186/1471-2105-4-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC149347/
https://www.ncbi.nlm.nih.gov/pubmed/12529185
http://dx.doi.org/10.1186/1471-2105-4-3

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