Effect of human leukocyte antigen heterozygosity on infectious disease outcome: The need for allele-specific measures

BACKGROUND: Doherty and Zinkernagel, who discovered that antigen presentation is restricted by the major histocompatibility complex (MHC, called HLA in humans), hypothesized that individuals heterozygous at particular MHC loci might be more resistant to particular infectious diseases than the corres...

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Detalles Bibliográficos
Autores principales: Lipsitch, Marc, Bergstrom, Carl T, Antia, Rustom
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC149356/
https://www.ncbi.nlm.nih.gov/pubmed/12542841
http://dx.doi.org/10.1186/1471-2350-4-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC149356/
https://www.ncbi.nlm.nih.gov/pubmed/12542841
http://dx.doi.org/10.1186/1471-2350-4-2

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