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Brn3c null mutant mice show long-term, incomplete retention of some afferent inner ear innervation

BACKGROUND: Ears of Brn3c null mutants develop immature hair cells, identifiable only by certain molecular markers, and undergo apoptosis in neonates. This partial development of hair cells could lead to enough neurotrophin expression to sustain sensory neurons through embryonic development. We have...

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Detalles Bibliográficos
Autores principales: Xiang, Mengqing, Maklad, Adel, Pirvola, Ulla, Fritzsch, Bernd
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC149366/
https://www.ncbi.nlm.nih.gov/pubmed/12585968
http://dx.doi.org/10.1186/1471-2202-4-2