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Dissociation of DNA damage and mitochondrial injury caused by hydrogen peroxide in SV-40 transformed lung epithelial cells

BACKGROUND: Since lung epithelial cells are constantly being exposed to reactive oxygen intermediates (ROIs), the alveolar surface is a major site of oxidative stress, and each cell type may respond differently to oxidative stress. We compared the extent of oxidative DNA damage with that of mitochon...

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Detalles Bibliográficos
Autores principales: Fujii, Yoshihiro, Tomita, Katsuyuki, Sano, Hiroyuki, Yamasaki, Akira, Hitsuda, Yutaka, Adcock, Ian M, Shimizu, Eiji
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC149434/
https://www.ncbi.nlm.nih.gov/pubmed/12495439
http://dx.doi.org/10.1186/1475-2867-2-16