DC-SIGN on B Lymphocytes Is Required For Transmission of HIV-1 to T Lymphocytes

Infection of T cells by HIV-1 can occur through binding of virus to dendritic cell (DC)-specific ICAM-3 grabbing nonintegrin (DC-SIGN) on dendritic cells and transfer of virus to CD4(+) T cells. Here we show that a subset of B cells in the blood and tonsils of normal donors expressed DC-SIGN, and th...

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Detalles Bibliográficos
Autores principales: Rappocciolo, Giovanna, Piazza, Paolo, Fuller, Craig L, Reinhart, Todd A, Watkins, Simon C, Rowe, David T, Jais, Mariel, Gupta, Phalguni, Rinaldo, Charles R
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1500807/
https://www.ncbi.nlm.nih.gov/pubmed/16839201
http://dx.doi.org/10.1371/journal.ppat.0020070

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1500807/
https://www.ncbi.nlm.nih.gov/pubmed/16839201
http://dx.doi.org/10.1371/journal.ppat.0020070

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