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Intronic Alternative Splicing Regulators Identified by Comparative Genomics in Nematodes

Many alternative splicing events are regulated by pentameric and hexameric intronic sequences that serve as binding sites for splicing regulatory factors. We hypothesized that intronic elements that regulate alternative splicing are under selective pressure for evolutionary conservation. Using a Wob...

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Detalles Bibliográficos
Autores principales: Kabat, Jennifer L, Barberan-Soler, Sergio, McKenna, Paul, Clawson, Hiram, Farrer, Tracy, Zahler, Alan M
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1500816/
https://www.ncbi.nlm.nih.gov/pubmed/16839192
http://dx.doi.org/10.1371/journal.pcbi.0020086