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Wiggle—Predicting Functionally Flexible Regions from Primary Sequence

The Wiggle series are support vector machine–based predictors that identify regions of functional flexibility using only protein sequence information. Functionally flexible regions are defined as regions that can adopt different conformational states and are assumed to be necessary for bioactivity....

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Detalles Bibliográficos
Autores principales: Gu, Jenny, Gribskov, Michael, Bourne, Philip E
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1500818/
https://www.ncbi.nlm.nih.gov/pubmed/16839194
http://dx.doi.org/10.1371/journal.pcbi.0020090