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Comprehensive thermodynamic analysis of 3′ double-nucleotide overhangs neighboring Watson–Crick terminal base pairs

Thermodynamic parameters are reported for duplex formation of 48 self-complementary RNA duplexes containing Watson–Crick terminal base pairs (GC, AU and UA) with all 16 possible 3′ double-nucleotide overhangs; mimicking the structures of short interfering RNAs (siRNA) and microRNAs (miRNA). Based on...

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Detalles Bibliográficos
Autores principales: O'Toole, Amanda S., Miller, Stacy, Haines, Nathan, Zink, M. Coleen, Serra, Martin J.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1500867/
https://www.ncbi.nlm.nih.gov/pubmed/16820533
http://dx.doi.org/10.1093/nar/gkl428