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Protease nexin-1 expression is altered in human breast cancer

BACKGROUND: Urokinase-type Plasminogen Activator (uPA), a serine protease, plays a pivotal role in human breast cancer metastasis by mediating the degradation of extracellular matrix proteins and promoting cell motility. In more advanced breast cancers, uPA activity is significantly up regulated and...

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Detalles Bibliográficos
Autores principales: Candia, Britny J, Hines, William C, Heaphy, Christopher M, Griffith, Jeffrey K, Orlando, Robert A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1501059/
https://www.ncbi.nlm.nih.gov/pubmed/16737540
http://dx.doi.org/10.1186/1475-2867-6-16