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Efficacy of topical cobalt chelate CTC-96 against adenovirus in a cell culture model and against adenovirus keratoconjunctivitis in a rabbit model

BACKGROUND: Adenovirus (Ad), associated with significant morbidity, has no topical treatment. A leading CTC compound (CTC-96), a Co(III )chelate, was found to have potent in vitro and in vivo antiviral efficacy against herpes viruses. In this study CTC-96 is being tested for possible anti-Adenovirus...

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Detalles Bibliográficos
Autores principales: Epstein, Seth P, Pashinsky, Yevgenia Y, Gershon, David, Winicov, Irene, Srivilasa, Charlie, Kristic, Katarina J, Asbell, Penny A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1502138/
https://www.ncbi.nlm.nih.gov/pubmed/16753060
http://dx.doi.org/10.1186/1471-2415-6-22