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Expression, Purification and Characterization of Ricin vectors used for exogenous antigen delivery into the MHC Class I presentation pathway

Disarmed versions of the cytotoxin ricin can deliver fused peptides into target cells leading to MHC class I-restricted antigen presentation [Smith et al. J Immunol 2002; 169:99-107]. The ricin delivery vector must contain an attenuated catalytic domain to prevent target cell death, and the fused pe...

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Detalles Bibliográficos
Autores principales: Smith, Daniel C., Marsden, Catherine J., Lord, J. Michael, Roberts, Lynne M.
Formato: Texto
Lenguaje:English
Publicado: Biological Procedures Online 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC150387/
https://www.ncbi.nlm.nih.gov/pubmed/12734560
http://dx.doi.org/10.1251/bpo42