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Expression, Purification and Characterization of Ricin vectors used for exogenous antigen delivery into the MHC Class I presentation pathway
Disarmed versions of the cytotoxin ricin can deliver fused peptides into target cells leading to MHC class I-restricted antigen presentation [Smith et al. J Immunol 2002; 169:99-107]. The ricin delivery vector must contain an attenuated catalytic domain to prevent target cell death, and the fused pe...
Autores principales: | Smith, Daniel C., Marsden, Catherine J., Lord, J. Michael, Roberts, Lynne M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Biological Procedures Online
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC150387/ https://www.ncbi.nlm.nih.gov/pubmed/12734560 http://dx.doi.org/10.1251/bpo42 |
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