Insulin utilizes the PI 3-kinase pathway to inhibit SP-A gene expression in lung epithelial cells

BACKGROUND: It has been proposed that high insulin levels may cause delayed lung development in the fetuses of diabetic mothers. A key event in lung development is the production of adequate amounts of pulmonary surfactant. Insulin inhibits the expression of surfactant protein A (SP-A), the major su...

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Detalles Bibliográficos
Autores principales: Miakotina, Olga L, Goss, Kelli L, Snyder, Jeanne M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2002
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC150512/
https://www.ncbi.nlm.nih.gov/pubmed/12537604
http://dx.doi.org/10.1186/rr191

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC150512/
https://www.ncbi.nlm.nih.gov/pubmed/12537604
http://dx.doi.org/10.1186/rr191

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