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Insulin utilizes the PI 3-kinase pathway to inhibit SP-A gene expression in lung epithelial cells
BACKGROUND: It has been proposed that high insulin levels may cause delayed lung development in the fetuses of diabetic mothers. A key event in lung development is the production of adequate amounts of pulmonary surfactant. Insulin inhibits the expression of surfactant protein A (SP-A), the major su...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2002
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC150512/ https://www.ncbi.nlm.nih.gov/pubmed/12537604 http://dx.doi.org/10.1186/rr191 |