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Do distribution volumes and clearances relate to tissue volumes and blood flows? A computer simulation
BACKGROUND: Kinetics of inhaled agents are often described by physiological models. However, many pharmacokinetic concepts, such as context-sensitive half-times, have been developed for drugs described by classical compartmental models. We derived classical compartmental models that describe the cou...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2006
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1508141/ https://www.ncbi.nlm.nih.gov/pubmed/16772041 http://dx.doi.org/10.1186/1471-2253-6-7 |