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Genomic patterns of pathogen evolution revealed by comparison of Burkholderia pseudomallei, the causative agent of melioidosis, to avirulent Burkholderia thailandensis

BACKGROUND: The Gram-negative bacterium Burkholderia pseudomallei (Bp) is the causative agent of the human disease melioidosis. To understand the evolutionary mechanisms contributing to Bp virulence, we performed a comparative genomic analysis of Bp K96243 and B. thailandensis (Bt) E264, a closely r...

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Detalles Bibliográficos
Autores principales: Yu, Yiting, Kim, H Stanley, Chua, Hui Hoon, Lin, Chi Ho, Sim, Siew Hoon, Lin, Daoxun, Derr, Alan, Engels, Reinhard, DeShazer, David, Birren, Bruce, Nierman, William C, Tan, Patrick
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1508146/
https://www.ncbi.nlm.nih.gov/pubmed/16725056
http://dx.doi.org/10.1186/1471-2180-6-46