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Histone Deacetylase Enzymes as Potential Drug Targets in Cancer and Parasitic Diseases
The elucidation of the mechanisms of transcriptional activation and repression in eukaryotic cells has shed light on the important role of acetylation-deacetylation of histones mediated by histone acetyltransferases (HATs) and histone deacetylases (HDACs), respectively. Another group belonging to th...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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Hindawi Publishing Corporation
2006
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1510935/ https://www.ncbi.nlm.nih.gov/pubmed/16883049 http://dx.doi.org/10.1155/JBB/2006/13474 |