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The ORF1 Protein Encoded by LINE-1: Structure and Function During L1 Retrotransposition

LINE-1, or L1 is an autonomous non-LTR retrotransposon in mammals. Retrotransposition requires the function of the two, L1-encoded polypeptides, ORF1p and ORF2p. Early recognition of regions of homology between the predicted amino acid sequence of ORF2 and known endonuclease and reverse transcriptas...

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Detalles Bibliográficos
Autor principal: Martin, Sandra L.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1510943/
https://www.ncbi.nlm.nih.gov/pubmed/16877816
http://dx.doi.org/10.1155/JBB/2006/45621