Cloning and Expression of Human Membrane-Bound and Soluble Engineered T Cell Receptors for Immunotherapy

We report here the design and construction of several gene vectors for expression in mammalian cells of membrane-bound and soluble human T cell receptors (TR). We designed a vector (TR-ALPHA-IRES-TR-BETA pEF4) that encodes high-level expression of the full-length TR on the surface of T cells. Furthe...

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Detalles Bibliográficos
Autores principales: Alajez, Nehad M., Eghtesad, Saman, Finn, Olivera J.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2006
Materias:
Methods Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1510948/
https://www.ncbi.nlm.nih.gov/pubmed/16883054
http://dx.doi.org/10.1155/JBB/2006/68091

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1510948/
https://www.ncbi.nlm.nih.gov/pubmed/16883054
http://dx.doi.org/10.1155/JBB/2006/68091

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