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Cloning and Expression of Human Membrane-Bound and Soluble Engineered T Cell Receptors for Immunotherapy
We report here the design and construction of several gene vectors for expression in mammalian cells of membrane-bound and soluble human T cell receptors (TR). We designed a vector (TR-ALPHA-IRES-TR-BETA pEF4) that encodes high-level expression of the full-length TR on the surface of T cells. Furthe...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Hindawi Publishing Corporation
2006
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1510948/ https://www.ncbi.nlm.nih.gov/pubmed/16883054 http://dx.doi.org/10.1155/JBB/2006/68091 |