Characterization of skeletal phenotypes of TRα1(PV) and TRβ(PV) mutant mice: implications for tissue thyroid status and T3 target gene expression

Bone development is extremely sensitive to alterations in thyroid status. Recently, we analyzed the skeletal phenotypes of mice with the dominant negative resistance to thyroid hormone (RTH) mutation PV targeted to either the thyroid hormone receptor (TR) α1 or β gene. This perspective summarizes ou...

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Detalles Bibliográficos
Autores principales: O'Shea, Patrick J., Bassett, J.H. Duncan, Cheng, Sheue-yann, Williams, Graham R.
Formato: Texto
Lenguaje:English
Publicado: The Nuclear Receptor Signaling Atlas 2006
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1513065/
https://www.ncbi.nlm.nih.gov/pubmed/16862217
http://dx.doi.org/10.1621/nrs.04011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1513065/
https://www.ncbi.nlm.nih.gov/pubmed/16862217
http://dx.doi.org/10.1621/nrs.04011

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