Thyroid hormone mediated changes in gene expression can be initiated by cytosolic action of the thyroid hormone receptor β through the phosphatidylinositol 3-kinase pathway

Thyroid hormone (TH) action is mediated principally through binding of the hormone ligand, 3,3,5-triiodothyronine (T(3)), to TH receptors (TRs). This hormone-receptor interaction recruits other proteins to form complexes that regulate gene expression by binding to DNA sequences in the promoter of ta...

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Detalles Bibliográficos
Autores principales: Moeller, Lars C., Cao, Xia, Dumitrescu, Alexandra M., Seo, Hisao, Refetoff, Samuel
Formato: Texto
Lenguaje:English
Publicado: The Nuclear Receptor Signaling Atlas 2006
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1513074/
https://www.ncbi.nlm.nih.gov/pubmed/16862226
http://dx.doi.org/10.1621/nrs.04020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1513074/
https://www.ncbi.nlm.nih.gov/pubmed/16862226
http://dx.doi.org/10.1621/nrs.04020

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