In vivo – in vitro toxicogenomic comparison of TCDD-elicited gene expression in Hepa1c1c7 mouse hepatoma cells and C57BL/6 hepatic tissue

BACKGROUND: In vitro systems have inherent limitations in their ability to model whole organism gene responses, which must be identified and appropriately considered when developing predictive biomarkers of in vivo toxicity. Systematic comparison of in vitro and in vivo temporal gene expression prof...

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Detalles Bibliográficos
Autores principales: Dere, Edward, Boverhof, Darrell R, Burgoon, Lyle D, Zacharewski, Timothy R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1513214/
https://www.ncbi.nlm.nih.gov/pubmed/16611356
http://dx.doi.org/10.1186/1471-2164-7-80

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1513214/
https://www.ncbi.nlm.nih.gov/pubmed/16611356
http://dx.doi.org/10.1186/1471-2164-7-80

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