RhoA signaling modulates cyclin D1 expression in human lung fibroblasts; implications for idiopathic pulmonary fibrosis

BACKGROUND: Idiopathic Pulmonary Fibrosis (IPF) is a debilitating disease characterized by exaggerated extracellular matrix deposition and aggressive lung structural remodeling. Disease pathogenesis is driven by fibroblastic foci formation, consequent on growth factor overexpression and myofibroblas...

Descripción completa

Detalles Bibliográficos
Autores principales: Watts, KL, Cottrell, E, Hoban, PR, Spiteri, MA
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1513217/
https://www.ncbi.nlm.nih.gov/pubmed/16776827
http://dx.doi.org/10.1186/1465-9921-7-88

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1513217/
https://www.ncbi.nlm.nih.gov/pubmed/16776827
http://dx.doi.org/10.1186/1465-9921-7-88

Ejemplares similares