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RhoA signaling modulates cyclin D1 expression in human lung fibroblasts; implications for idiopathic pulmonary fibrosis

BACKGROUND: Idiopathic Pulmonary Fibrosis (IPF) is a debilitating disease characterized by exaggerated extracellular matrix deposition and aggressive lung structural remodeling. Disease pathogenesis is driven by fibroblastic foci formation, consequent on growth factor overexpression and myofibroblas...

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Detalles Bibliográficos
Autores principales:	Watts, KL, Cottrell, E, Hoban, PR, Spiteri, MA
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2006
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1513217/ https://www.ncbi.nlm.nih.gov/pubmed/16776827 http://dx.doi.org/10.1186/1465-9921-7-88

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