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Overexpression of connexin 43 using a retroviral vector improves electrical coupling of skeletal myoblasts with cardiac myocytes in vitro

BACKGROUND: Organ transplantation is presently often the only available option to repair a damaged heart. As heart donors are scarce, engineering of cardiac grafts from autologous skeletal myoblasts is a promising novel therapeutic strategy. The functionality of skeletal muscle cells in the heart mi...

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Detalles Bibliográficos
Autores principales: Tolmachov, Oleg, Ma, Yu-Ling, Themis, Michael, Patel, Pravina, Spohr, Hilmar, MacLeod, Kenneth T, Ullrich, Nina D, Kienast, Yvonne, Coutelle, Charles, Peters, Nicholas S
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1513252/
https://www.ncbi.nlm.nih.gov/pubmed/16756651
http://dx.doi.org/10.1186/1471-2261-6-25