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Uncoupling of ATP-Mediated Calcium Signaling and Dysregulated Interleukin-6 Secretion in Dendritic Cells by Nanomolar Thimerosal

Dendritic cells (DCs), a rare cell type widely distributed in the soma, are potent antigen-presenting cells that initiate primary immune responses. DCs rely on intracellular redox state and calcium (Ca(2+)) signals for proper development and function, but the relationship between these two signaling...

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Detalles Bibliográficos
Autores principales: Goth, Samuel R., Chu, Ruth A., Gregg, Jeffrey P., Cherednichenko, Gennady, Pessah, Isaac N.
Formato: Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1513334/
https://www.ncbi.nlm.nih.gov/pubmed/16835063
http://dx.doi.org/10.1289/ehp.8881