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Uncoupling of ATP-Mediated Calcium Signaling and Dysregulated Interleukin-6 Secretion in Dendritic Cells by Nanomolar Thimerosal
Dendritic cells (DCs), a rare cell type widely distributed in the soma, are potent antigen-presenting cells that initiate primary immune responses. DCs rely on intracellular redox state and calcium (Ca(2+)) signals for proper development and function, but the relationship between these two signaling...
Autores principales: | Goth, Samuel R., Chu, Ruth A., Gregg, Jeffrey P., Cherednichenko, Gennady, Pessah, Isaac N. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
National Institute of Environmental Health Sciences
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1513334/ https://www.ncbi.nlm.nih.gov/pubmed/16835063 http://dx.doi.org/10.1289/ehp.8881 |
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