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Dpb11, the budding yeast homolog of TopBP1, functions with the checkpoint clamp in recombination repair

Dpb11 is required for the loading of DNA polymerases α and ɛ on to DNA in chromosomal DNA replication and interacts with the DNA damage checkpoint protein Ddc1 in Saccharomyces cerevisiae. The interaction between the homologs of Dpb11 and Ddc1 in human cells and fission yeast is thought to reflect t...

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Detalles Bibliográficos
Autores principales: Ogiwara, Hideaki, Ui, Ayako, Onoda, Fumitoshi, Tada, Shusuke, Enomoto, Takemi, Seki, Masayuki
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1513344/
https://www.ncbi.nlm.nih.gov/pubmed/16840526
http://dx.doi.org/10.1093/nar/gkl411