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Dpb11, the budding yeast homolog of TopBP1, functions with the checkpoint clamp in recombination repair
Dpb11 is required for the loading of DNA polymerases α and ɛ on to DNA in chromosomal DNA replication and interacts with the DNA damage checkpoint protein Ddc1 in Saccharomyces cerevisiae. The interaction between the homologs of Dpb11 and Ddc1 in human cells and fission yeast is thought to reflect t...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2006
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1513344/ https://www.ncbi.nlm.nih.gov/pubmed/16840526 http://dx.doi.org/10.1093/nar/gkl411 |