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The relation between deoxycytidine kinase activity and the radiosensitising effect of gemcitabine in eight different human tumour cell lines

BACKGROUND: Gemcitabine (dFdC) is an active antitumour agent with radiosensitising properties, shown both in preclinical and clinical studies. In the present study, the relation between deoxycytidine kinase (dCK) activity and the radiosensitising effect of gemcitabine was investigated in eight diffe...

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Detalles Bibliográficos
Autores principales: Pauwels, Bea, Korst, Annelies EC, Pattyn, Greet GO, Lambrechts, Hilde AJ, Kamphuis, Juliette AE, De Pooter, Christel MJ, Peters, Godefridus J, Lardon, Filip, Vermorken, Jan B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1513392/
https://www.ncbi.nlm.nih.gov/pubmed/16734894
http://dx.doi.org/10.1186/1471-2407-6-142