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Detection of atovaquone-proguanil resistance conferring mutations in Plasmodium falciparum cytochrome b gene in Luanda, Angola

BACKGROUND: The fixed dose combination atovaquone-proguanil is a recently introduced antimalarial for treatment and prophylaxis of Plasmodium falciparum malaria. It is highly effective with a good tolerability profile and a convenient prophylactic regimen. Nevertheless, cases of treatment failure ha...

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Detalles Bibliográficos
Autores principales: Pimentel, Sónia, Nogueira, Fátima, Benchimol, Carla, Quinhentos, Vatúsia, Bom, Joana, Varandas, Luís, do Rosário, Virgílio, Bernardino, Luís
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1513587/
https://www.ncbi.nlm.nih.gov/pubmed/16597338
http://dx.doi.org/10.1186/1475-2875-5-30