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Subfamily logos: visualization of sequence deviations at alignment positions with high information content

BACKGROUND: Recognition of relevant sequence deviations can be valuable for elucidating functional differences between protein subfamilies. Interesting residues at highly conserved positions can then be mutated and experimentally analyzed. However, identification of such sites is tedious because aut...

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Detalles Bibliográficos
Autor principal: Beitz, Eric
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1513608/
https://www.ncbi.nlm.nih.gov/pubmed/16790056
http://dx.doi.org/10.1186/1471-2105-7-313